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The Journal of General Physiology, Vol 21, 93-105, Copyright © 1937 by The Rockefeller University Press

ARTICLE

VISUAL ADAPTATION AND CHEMISTRY OF THE RODS

George Wald 1 and Anna-Betty Clark 1

1 From the Biological Laboratories, Harvard University, Cambridge

1. The reality of a chemical cycle proposed to describe the rhodopsin system is tested with dark adaptation measurements.

2. The first few minutes of rod dark adaptation are rapid following short, slower following long irradiation. As dark adaptation proceeds, the slow process grows more prominent, and occupies completely the final stages of adaptation.

3. Light adaptation displays similar duality. As the exposure to light of constant intensity lengthens, the visual threshold rises, and independently the speed of dark adaptation decreases.

4. These results conform with predictions from the chemical equations.

 Accepted on July 1, 1937


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