|
||
ARTICLE |
The prevalent probabilistic view is virtually untestable; it remains a plausible belief. The cases usually cited can not be taken as evidence for it. Several grounds for this conclusion are developed. Three issues are distinguished in an attempt to clarify a murky debate: (a) the utility of probabilistic methods in data reduction, (b) the value of models that assume indeterminacy, and (c) the validity of the inference that the nervous system is largely indeterministic at the neuronal level. No exception is taken to the first two; the second is a private heuristic question. The third is the issue to which the assertion in the first two sentences is addressed. Of the two kinds of uncertainty, statistical mechanical (= practical unpredictability) as in a gas, and Heisenbergian indeterminancy, the first certainly exists, the second is moot at the neuronal level. It would contribute to discussion to recognize that neurons perform with a degree of reliability. Although unreliability is difficult to establish, to say nothing of measure, evidence that some neurons have a high degree of reliability, in both connections and activity is increasing greatly. An example is given from sternarchine electric fish.
This article has been cited by other articles:
![]() |
C. R. Turner, M. Derylo, C. D. de Santana, J. A. Alves-Gomes, and G. T. Smith Phylogenetic comparative analysis of electric communication signals in ghost knifefishes (Gymnotiformes: Apteronotidae) J. Exp. Biol., December 1, 2007; 210(23): 4104 - 4122. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. T. Moortgat, T. H. Bullock, and T. J. Sejnowski Precision of the Pacemaker Nucleus in a Weakly Electric Fish: Network Versus Cellular Influences J Neurophysiol, February 1, 2000; 83(2): 971 - 983. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. T. Moortgat, T. H. Bullock, and T. J. Sejnowski Gap Junction Effects on Precision and Frequency of a Model Pacemaker Network J Neurophysiol, February 1, 2000; 83(2): 984 - 997. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. Azouz and C. M. Gray Cellular Mechanisms Contributing to Response Variability of Cortical Neurons In Vivo J. Neurosci., March 15, 1999; 19(6): 2209 - 2223. [Abstract] [Full Text] [PDF] |
||||
![]() |
W Metzner Neural circuitry for communication and jamming avoidance in gymnotiform electric fish J. Exp. Biol., January 5, 1999; 202(10): 1365 - 1375. [Abstract] [PDF] |
||||
![]() |
H Zakon, L Mcanelly, G. Smith, K Dunlap, G Lopreato, J Oestreich, and W. Few Plasticity of the electric organ discharge: implications for the regulation of ionic currents J. Exp. Biol., January 5, 1999; 202(10): 1409 - 1416. [Abstract] [PDF] |
||||
![]() |
K. T. Moortgat, C. H. Keller, T. H. Bullock, and T. J. Sejnowski Submicrosecond pacemaker precision is behaviorally modulated: The gymnotiform electromotor pathway PNAS, April 14, 1998; 95(8): 4684 - 4689. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. J. Berry, D. K. Warland, and M. Meister The structure and precision of retinal spike trains PNAS, May 13, 1997; 94(10): 5411 - 5416. [Abstract] [Full Text] [PDF] |
||||
![]() |
Z. Mainen and T. Sejnowski Reliability of spike timing in neocortical neurons Science, June 9, 1995; 268(5216): 1503 - 1506. [Abstract] [PDF] |
||||
![]() |
C. D. Hopkins Sex Differences in Electric Signaling in an Electric Fish Science, June 2, 1972; 176(4038): 1035 - 1037. [Abstract] [PDF] |
||||
|
|