|
|
|
|
|
|
|
||
The Journal of General Physiology, Vol 76, 213-231, Copyright © 1980 by The Rockefeller University Press
ARTICLES |
JE Zengel, KL Magleby, JP Horn, DA McAfee and PJ Yarowsky
The effect of repetitive stimulation on synaptic transmission was studied in the isolated superior cervical ganglion of the rabbit under conditions of reduced quantal content. Excitatory postsynaptic potentials (EPSP) were recorded with the sucrose gap technique to obtain estimates of transmitter release. Four components of increased transmitter release, with time constants of decay similar to those observed at the frog neuromuscular junction at 20 degrees C, were found in the ganglion at 34 degrees C: a first component of facilitation, which decayed with a time constant of 59 +/- 14 ms (mean +/- SD); a second component of facilitation, which decayed with a time constant of 388 +/- 97 ms; augmentation, which decayed with a time constant of 7.2 +/- 1 s; and potentiation, which decayed with a time constant of 88 +/- 25 s. The addition of 0.1-0.2 mM Ba2+ to the Locke solution increased the magnitude but not the time constant of decay of augmentation. Ba2+ had little effect on potentiation. The addition of 0.2-0.8 mM Sr2+ to the Locke solution appeared to increase the magnitude of the second component of facilitation. Sr2+ had little effect on augmentation or potentiation. These selective effects of Ba2+ and Sr2+ on the components of increased transmitter release in the rabbit ganglion are similar to the effects of these ions at the frog neuromuscular junction. Although the effects of Ba2+ and Sr2+ are similar in the two preparations, the magnitudes of augmentation and the second component of facilitation after a single impulse were about 6-10 times greater in the rabbit ganglion than at the frog neuromuscular junction. These results suggest that the underlying mechanisms in the nerve terminal that give rise to the components of increased transmitter release in the rabbit ganglion and frog neuromuscular junction are similar but not identical.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Facebook 
Reddit 
Technorati 
Twitter What's this?
This article has been cited by other articles:
|
|
 |
|
  R. L. P. Habets and J. G. G. Borst Dynamics of the readily releasable pool during post-tetanic potentiation in the rat calyx of Held synapse J. Physiol., June 1, 2007; 581(2): 467 - 478. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. L. P Habets and J. G. G Borst Post-tetanic potentiation in the rat calyx of Held synapse J. Physiol., April 1, 2005; 564(1): 173 - 187. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. M. Kalkstein and K. L. Magleby Augmentation Increases Vesicular Release Probability in the Presence of Masking Depression at the Frog Neuromuscular Junction J. Neurosci., December 15, 2004; 24(50): 11391 - 11403. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Fuhrmann, A. Cowan, I. Segev, M. Tsodyks, and C. Stricker Multiple mechanisms govern the dynamics of depression at neocortical synapses of young rats J. Physiol., June 1, 2004; 557(2): 415 - 438. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. E. Fox and P. E. Lloyd Evidence That Post-Tetanic Potentiation Is Mediated by Neuropeptide Release in Aplysia J Neurophysiol, December 1, 2001; 86(6): 2845 - 2855. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. A. Aileru, A. De Albuquerque, J. M. Hamlyn, P. Manunta, J. R. Shah, M. J. Hamilton, and D. Weinreich Synaptic plasticity in sympathetic ganglia from acquired and inherited forms of ouabain-dependent hypertension Am J Physiol Regulatory Integrative Comp Physiol, August 1, 2001; 281(2): R635 - R644. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. S. Fitzpatrick, G. Akopian, and J. P. Walsh Short-Term Plasticity at Inhibitory Synapses in Rat Striatum and Its Effects on Striatal Output J Neurophysiol, May 1, 2001; 85(5): 2088 - 2099. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. S. Dittman, A. C. Kreitzer, and W. G. Regehr Interplay between Facilitation, Depression, and Residual Calcium at Three Presynaptic Terminals J. Neurosci., February 15, 2000; 20(4): 1374 - 1385. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X.-Y. Jiang and T. W. Abrams Use-Dependent Decline of Paired-Pulse Facilitation at Aplysia Sensory Neuron Synapses Suggests a Distinct Vesicle Pool or Release Mechanism J. Neurosci., December 15, 1998; 18(24): 10310 - 10319. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
O. Sacchi, M. L. Rossi, R. Canella, and R. Fesce Synaptic Current at the Rat Ganglionic Synapse and Its Interactions With the Neuronal Voltage-Dependent Currents J Neurophysiol, February 1, 1998; 79(2): 727 - 742. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-H. Wang and P. T. Kelly Attenuation of Paired-Pulse Facilitation Associated With Synaptic Potentiation Mediated by Postsynaptic Mechanisms J Neurophysiol, November 1, 1997; 78(5): 2707 - 2716. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. M. Fischer, R. S. Zucker, and T. J. Carew Activity-Dependent Potentiation of Synaptic Transmission From L30 Inhibitory Interneurons of Aplysia Depends on Residual Presynaptic Ca2+ But Not on Postsynaptic Ca2+ J Neurophysiol, October 1, 1997; 78(4): 2061 - 2071. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. A. Castro-Alamancos and B. W. Connors Distinct forms of short-term plasticity at excitatory synapses of hippocampus and neocortex PNAS, April 15, 1997; 94(8): 4161 - 4166. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Kelso SR and T. Brown Differential conditioning of associative synaptic enhancement in hippocampal brain slices Science, April 4, 1986; 232(4746): 85 - 87. [Abstract] [PDF]
|
|
|
|
|
|
T. Brown and D. McAfee Long-term synaptic potentiation in the superior cervical ganglion Science, March 12, 1982; 215(4538): 1411 - 1413. [Abstract] [PDF]
|
|
|
|
