The Journal of General Physiology
Avanti Polar Lipids, Inc.
  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents
This Article
Right arrow Full Text (PDF, 693K)
Right arrow Alert me when this article is cited
Right arrow Citation Map
Services
Right arrow Email this article
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new content in the JGP
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Begenisich, T.
Right arrow Articles by Busath, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Begenisich, T.
Right arrow Articles by Busath, D.
Right arrowPubmed/NCBI databases
*Compound via MeSH
*Substance via MeSH
Hazardous Substances DB
*SODIUM
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Facebook   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

The Journal of General Physiology, Vol 77, 489-502, Copyright © 1981 by The Rockefeller University Press

ARTICLES

Sodium flux ratio in voltage-clamped squid giant axons

T Begenisich and D Busath

The sodium flux ratio across the axolemma of internally perfused, voltage-clamped giant axons of Loligo pealei has been measured at various membrane potentials. The flux ratio exponent obtained from these measurements was about unity and independent of membrane voltage over the 50 mV range from about -20 to l mV. These results, combined with previous measurements of ion permeation through sodium channels, show that the sodium channel behaves like a multi-ion pore with two ion binding sites that are rarely simultaneously occupied by sodium.
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 JGPHome page
R.F. Rakowski, P. Artigas, F. Palma, M. Holmgren, P. De Weer, and D. C. Gadsby
Sodium Flux Ratio in Na/K Pump-Channels Opened by Palytoxin
J. Gen. Physiol., July 1, 2007; 130(1): 41 - 54.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
R. A. Li, K. Hui, R. J. French, K. Sato, C. A. Henrikson, G. F. Tomaselli, and E. Marban
Dependence of {micro}-Conotoxin Block of Sodium Channels on Ionic Strength but Not on the Permeating [Na+]: IMPLICATIONS FOR THE DISTINCTIVE MECHANISTIC INTERACTIONS BETWEEN Na+ AND K+ CHANNEL PORE-BLOCKING TOXINS AND THEIR MOLECULAR TARGETS
J. Biol. Chem., August 15, 2003; 278(33): 30912 - 30919.
[Abstract] [Full Text] [PDF]

Home page
 JGPHome page
C.-C. Kuo, T.-J. Lin, and C.-P. Hsieh
Effect of Na+ Flow on Cd2+ Block of Tetrodotoxin-resistant Na+ Channels
J. Gen. Physiol., July 30, 2002; 120(2): 159 - 172.
[Abstract] [Full Text] [PDF]

Home page
 JGPHome page
R. F. Rakowski, D. C. Gadsby, and P. De Weer
Single Ion Occupancy and Steady-state Gating of Na Channels in Squid Giant Axon
J. Gen. Physiol., March 1, 2002; 119(3): 235 - 250.
[Abstract] [Full Text] [PDF]

Home page
 JGPHome page
L. P. Wollmuth and B. Sakmann
Different Mechanisms of Ca2+ Transport in NMDA and Ca2+-permeable AMPA Glutamate Receptor Channels
J. Gen. Physiol., November 1, 1998; 112(5): 623 - 636.
[Abstract] [Full Text] [PDF]


  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents