The Journal of General Physiology
Scientifica: Experts in Electrophysiology
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The Journal of General Physiology, Vol 78, 201-229, Copyright © 1981 by The Rockefeller University Press

ARTICLES

The kinetics of monazomycin-induced voltage-dependent conductance. II. Theory and a demonstration of a form of memory

RU Muller and CS Peskin

The empirical differential equation that describes the kinetics of monazomycin-induced voltage-dependent conductance is derived using a standard chemical kinetic formulation and the assumption that monazomycin entry into and exit from the membrane is autocatalytic. The predicted form of gating currents is shown and numerical calculations for this process are made using a range of values for two unmeasured variables. A form of "memory" is then demonstrated, along with the ability of the theoretical equation to explain the nature of the memory.
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