The Journal of General Physiology
Cell MicroControls
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Index of Online Supplemental Material for
J. Gen. Physiol. 10.1085/jgp.200308876
Isaev et al.

Figure S1 Ionic currents in a tsA201 cell expressing NCX1.1 and the wild-type CaV1.2 channels.

Figure S2 The exchanger current has little effect on the measurement of asymmetric ionic and gating currents.

Figure S3 Estimation of the gating charge during a voltage pulse near the reversal potential.

Figure S4 Comparison of activation properties of the whole cell calcium currents through the wild-type CaV1.2 channels (n = 8) and the {Delta}1733 carboxyl terminus deletion mutant (n = 6) transiently expressed in tsa201 cells.

Figure S5 Comparison of deactivation properties of the whole-cell calcium currents through the wild-type CaV1.2 channels (n = 8) and the {Delta}1733 carboxyl terminus deletion mutant (n = 6) transiently expressed in tsa201 cells.

Figure S6 The following model considers three allosterically coupled processes: voltage-dependent gating (rest-active transition), inactivation (primed-inactivated transition), and Ca binding (unbound Ca transition).





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