Computational Biology

Computational Biology

Integrative model of coronary flow in anatomically based vasculature under myogenic, shear, and metabolic regulation
Ravi Namani, Ghassan S. Kassab, Yoram Lanir

The Journal of General Physiology Jan 2018, 150 (1) 145-168; DOI: 10.1085/jgp.201711795
A new model for an old friend
Caitlin Sedwick

The Journal of General Physiology Dec 2017, 149 (12) 1059; DOI: 10.1085/jgp.201711941
Chasing the open-state structure of pentameric ligand-gated ion channels
Giovanni Gonzalez-Gutierrez, Yuhang Wang, Gisela D. Cymes, Emad Tajkhorshid, Claudio Grosman

The Journal of General Physiology Dec 2017, 149 (12) 1119-1138; DOI: 10.1085/jgp.201711803
Asymmetry of inverted-topology repeats in the AE1 anion exchanger suggests an elevator-like mechanism
Emel Ficici, José D. Faraldo-Gómez, Michael L. Jennings, Lucy R. Forrest

The Journal of General Physiology Dec 2017, 149 (12) 1149-1164; DOI: 10.1085/jgp.201711836
Modeling pacemaker deterioration with age
Caitlin Sedwick

The Journal of General Physiology Oct 2017, 149 (10) 891; DOI: 10.1085/jgp.201711869
Age-related pacemaker deterioration is due to impaired intracellular and membrane mechanisms: Insights from numerical modeling
Joachim Behar, Yael Yaniv

The Journal of General Physiology Oct 2017, 149 (10) 935-949; DOI: 10.1085/jgp.201711792
Quenching the spark: Termination of CICR in the submicroscopic space of the dyad
Mark B. Cannell, Cherrie H.T. Kong

The Journal of General Physiology Sep 2017, 149 (9) 837-845; DOI: 10.1085/jgp.201711807
The structure of binding curves and practical identifiability of equilibrium ligand-binding parameters
Thomas R. Middendorf, Richard W. Aldrich

The Journal of General Physiology Jan 2017, 149 (1) 121-147; DOI: 10.1085/jgp.201611703
Structural identifiability of equilibrium ligand-binding parameters
Thomas R. Middendorf, Richard W. Aldrich

The Journal of General Physiology Jan 2017, 149 (1) 105-119; DOI: 10.1085/jgp.201611702
Structure and mechanism of the ATP synthase membrane motor inferred from quantitative integrative modeling
Vanessa Leone, José D. Faraldo-Gómez

The Journal of General Physiology Dec 2016, 148 (6) 441-457; DOI: 10.1085/jgp.201611679

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