June 2014 | Volume 143, No. 6
- Functional ryanodine receptors in the membranes of neurohypophysial secretory granules
Localized calcium release from ryanodine-sensitive stores in large dense core vesicles may modulate secretion of neuropeptides from neurohypophysial terminals.
- Interactions between permeation and gating in the TMEM16B/anoctamin2 calcium-activated chloride channel
Extracellular anions more permeant than Cl− modulate TMEM16B gating to promote channel opening, whereas less permeant anions favor channel closure.
- Functional characterization of a Na+-dependent dicarboxylate transporter from Vibrio cholerae
VcINDY, a bacterial homolog of transporters implicated in lifespan in fruit flies and insulin resistance in mammals, is a high affinity, electrogenic, Na+-dependent dicarboxylate transporter.