December 2014 | Volume 144, No. 6
- Crystal structure of the sodium–proton antiporter NhaA dimer and new mechanistic insights
A dimeric structure of the sodium–proton antiporter NhaA provides insight into the roles of Asp163 and Lys300 in the transport mechanism.
- Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties
Volatile anesthetics act directly on neuronal sodium channels, independently of effects on the lipid bilayer.
- Juxtaposition of the changes in intracellular calcium and force during staircase potentiation at 30 and 37°C
Temperature-dependent changes in basal calcium and in the calcium transient contribute to force potentiation during repetitive stimulation.