August 2015 | Volume 146, No. 2
- Sphingomyelinase D inhibits store-operated Ca2+ entry in T lymphocytes by suppressing ORAI current
Sphingomyelinase D suppresses Orai current in human T cells and decreases cytokine production, providing a mechanism whereby certain bacteria could inhibit the immune system.
- A conserved structural mechanism of NMDA receptor inhibition: A comparison of ifenprodil and zinc
Zinc and ifenprodil induce similar conformational changes in the NMDA receptor, suggesting a conserved mechanism of inhibition independent of receptor subtype and the site at which the inhibitor binds.