About the Cover
Cover picture: The M2 domain selectivity filter region of the glycine
receptor channel (GlyR)with mutations that reverse ion selectivity.The anion-selective WT 1 GlyR (top)has a partially hydrated Cl ion closely interacting with the positive arginine residues (R0').
The cation-selective mutant GlyR (with A-1'E and P-2'
;bottom)has a more hydrated Na ion interacting with negative glutamate residues.
See related articles by Keramidas, A.,A.J. Moorhouse, K.D. Pierce, P.R. Schofield,
and P.H. Barry, in this issue, pp.
393-410,
and byMoorhouse, A.J., A. Keramidas, A. Zaykin, P.R. Schofield, and P.H.Barry,
in this issue,pp.411-425.
[Table of Contents]
