%0 Journal Article
%A Blair, H. A.
%T ON THE INTENSITY-TIME RELATIONS FOR STIMULATION BY ELECTRIC CURRENTS. I
%D 1932
%R 10.1085/jgp.15.6.709
%J The Journal of General Physiology
%P 709-729
%V 15
%N 6
%X Formulae are derived for the time-intensity relations for stimulation by direct currents using the following hypotheses: first, the current produces an excitatory effect whose rate of growth is proportional to the voltage; and second, the tissue reacts toward the normal state at a rate proportional to the amount of excitation. If p represents the local excitatory process numerically, the hypotheses are represented by the differential equation See PDF for Structure. where K and k are constants and V the applied voltage. For the stimulus to be adequate it is assumed that p must be built up to a certain liminal value. It appears as a deduction from the data that this liminal value is a function of the voltage of the form h ± αV where h and α are constants. α is zero or negligible for certain electrodes. αV is a measure of electrotonus or a similar phenomenon. Experimental data are discussed and are shown to agree satisfactorily with the derived formulae for stimulation both at the anode and cathode.
%U http://jgp.rupress.org/content/jgp/15/6/709.full.pdf