TABLE I

Single-Channel Properties of MEC-4d/10d Channels and Effects of Auxiliary Subunits

γ1 (pS)Po1γ2 (pS)Po2〈γ〉 (pS)Po
MEC-4d/10d19.3 ± 4.3 (11)0.38 ± 0.27 (11)29.3 ± 4.9 (11)0.42 ± 0.33 (11)17.0 ± 6.8 (11)0.72 ± 0.20 (11)
+MEC-2NDND38.3 ± 1.6 (8)aNA31.8 ± 7.2 (8)a0.79 ± 0.26 (8)
+MEC-6NDND30.2 ± 5.7 (6)NA24.9 ± 6.1 (6)a0.72 ± 0.42 (6)
+MEC-2 +MEC-623.1 ± 2.5 (5)0.46 ± 0.27 (5)36.3 ± 1.6 (5)a0.42 ± 0.29 (5)25.6 ± 5.3 (5)a0.89 ± 0.04 (5)
  • Po ANOVA: F(3,26) = 2.06, P = 0.13. γ ANOVA: F(3,24) = 9.3, P < 0.0005.

  • a P < 0.01 by one-way t test compared to MEC-4d/10d.