Table 1. Cryo-EM domain nomenclature of RyR1
Domain nameAlternative namesColoraSequenceb
N-terminal domainYellow1–627
SPRY1Light orange628–849
RY1 and 2P1Light magenta850–1,054
SPRY2 and 3Light orange1,055–1,656
JsolHandleGreen1,657–2,144
BsolHD1&2Cyan2,145–3,613
 Includes RY3 and 4P2Orange2,735–2,938
CsolCentral domainTomato3,667–4,174
 Includes EF hand motifs4,060–4,134
  TaF4,175–4,253
Transmembrane domainBlue4,541–4,956
C-terminal domainBrown4,957–5,037
  • a Domain color in Fig. 1.

  • b des Georges et al. (2016).