Table 1. Comparison of unitary channel currents and Po values at selected voltages of KcsAE71E channel from this study with data from the literature
SourceMean currentOpen probability
−100 mV100 mV−100 mV100 mV40 mV
This study−9.3 ± 1.36.5 ± 1.10.84 ± 0.10.91 ± 0.130.86 ± 0.11
Banerjee and Nimigean, 2011−12 ± 1.57.2 ± 10.97 ± 0.010.97 ± 0.02n.a.
Hirano et al., 2011n.a.n.a.n.a.n.a.0.85 ± 0.2
Zhao et al., 2015n.a.6.5n.a.0.98 ± 0.01n.a.

KcsAE71E was produced in E. coli (Banerjee and Nimigean, 2011; Hirano et al., 2011; Zhao et al., 2015) and reconstituted in PLBs from NDs (Banerjee and Nimigean, 2011) or via microsomes (Hirano et al., 2011; Zhao et al., 2015). In all cases, channel activity was recorded in bilayers containing anionic lipids in buffers with 100 mM K+, pH 4.0 (Banerjee and Nimigean, 2011; Zhao et al., 2015), or 200 mM K+, pH 4.0 (Hirano et al., 2011). Literature data were estimated from figures in respective publications. Data from this study are from Fig. 6. Information on current amplitudes or open probabilities, which is not available from the literature, is indicated by n.a. in the table.