Table 1. Boltzmann fit parameters for Kv2.1 and Kv2.1:Kv6.4 heteromers
ChannelActivation (GV)SSI
V50aSlopebV50SlopePedestalc
Kv2.1d7.2 ± 1.014.1 ± 0.3−10.5 ± 0.67.5 ± 0.40.67 ± 0.02
+ Kv6.4 WTe−12.8 ± 1.415.1 ± 0.4−62.6 ± 0.67.7 ± 0.20.28 ± 0.01
+ Kv6.4-PIPIIV-KV2.1 CTe−16.3 ± 0.514.2 ± 0.6−82.3 ± 1.412.2 ± 0.50.3 ± 0.01
  • a Midpoint of single Boltzmann fit in mV (mean ± SEM).

  • b Slope of single Boltzmann fit (mean ± SEM).

  • c Non-inactivating pedestal current fraction determined from Boltzmann fit (mean ± SEM).

  • d n = 7.

  • e n = 10.